ALTHEA Gold Libraries™: antibody libraries for therapeutic antibody discovery
نویسندگان
چکیده
منابع مشابه
Modern therapeutic antibody drug discovery technologies.
Aim and Scope: Therapeutic monoclonal antibodies have become one of the most important areas in the modern pharmaceutical industry, with more than $52B in value and year-on-year growth currently leading all therapeutic approaches in the industry. Therapeutic monoclonal antibody leads can be discovered from phage, bacterial, yeast, mammalian cell, or in vitro display libraries, from immune compe...
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Phage display involves the expression of selected proteins on the surface of filamentous phage through fusion with phage coat protein, with the genetic sequence packaged within, linking phenotype to genotype selection. When combined with antibody libraries, phage display allows for rapid in vitro selection of antigen-specific antibodies and recovery of their corresponding coding sequence. Large...
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ژورنال
عنوان ژورنال: mAbs
سال: 2019
ISSN: 1942-0862,1942-0870
DOI: 10.1080/19420862.2019.1571879